Search results for "Pharmaceutical Science"

showing 10 items of 2702 documents

Chemical Composition and Biological Activities of Prangos ferulacea Essential Oils

2022

Prangos ferulacea (L.) Lindl, which belongs to the Apiaceae family, is a species that mainly grows in the eastern Mediterranean region and in western Asia. It has been largely used in traditional medicine in several countries and it has been shown to possess several interesting biological properties. With the aim to provide new insights into the phytochemistry and pharmacology of this species, the essential oils of flowers and leaves from a local accession that grows in Sicily (Italy) and has not yet been previously studied were investigated. The chemical composition of both oils, obtained by hydrodistillation from the leaves and flowers, was evaluated by GC-MS. This analysis allowed us to …

(Z)-β-ocimenePrangos ferulaceaantimicrobial activityApiaceae; <i>Prangos ferulacea</i>; (<i>Z</i>)-<i>β</i>-ocimene; GC-MS; antioxidant activity; antimicrobial activityOrganic ChemistryPharmaceutical Scienceantioxidant activityAntioxidantsAnalytical ChemistryAnti-Bacterial AgentsPlant LeavesAnti-Infective AgentsChemistry (miscellaneous)Drug DiscoveryOils VolatileMolecular MedicinePhysical and Theoretical ChemistryGC-MSSicilyApiaceae
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2020

New soluble and intensely near-IR-absorbing transition metal (Ti, Zr, V, Ni) complexes were synthesized using a redox non-innocent N,N’-bis(3,5-di-tertbutyl-2-hydroxy-phenyl) -1,2-phenylenediamine (H4L) as a ligand precursor. In all the complexes, ([Ti(Lox)2, [Zr(Lox)2], [V(Lsq1)(HLox)] and [Ni(HLox)2], two organic molecules coordinate to the metal center as tri- or tetradentate ligands. The solid-state structures of the complexes were determined using single crystal XRD, and the compounds were further characterized with Electrospray Ionisation Mass Spectrometry (ESI-MS). Thermoanalytical measurements indicated the thermal stabilities of the complexes. All compounds absorb strongly in the n…

010405 organic chemistryChemistryLigandOrganic ChemistryPharmaceutical Science010402 general chemistryMass spectrometryElectrochemistry01 natural sciencesRedoxNon-innocent ligand0104 chemical sciencesAnalytical ChemistryMetalCrystallographyTransition metalChemistry (miscellaneous)visual_artDrug Discoveryvisual_art.visual_art_mediumMolecular MedicinePhysical and Theoretical ChemistrySingle crystalMolecules
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Cnidarian Interaction with Microbial Communities: From Aid to Animal’s Health to Rejection Responses

2018

The phylum Cnidaria is an ancient branch in the tree of metazoans. Several species exert a remarkable longevity, suggesting the existence of a developed and consistent defense mechanism of the innate immunity capable to overcome the potential repeated exposure to microbial pathogenic agents. Increasing evidence indicates that the innate immune system in Cnidarians is not only involved in the disruption of harmful microorganisms, but also is crucial in structuring tissue-associated microbial communities that are essential components of the Cnidarian holobiont and useful to the animal&rsquo;s health for several functions, including metabolism, immune defense, development, and behavior. Someti…

0106 biological sciences0301 basic medicineCnidariaMicrobial communitiemedia_common.quotation_subjectPharmaceutical Sciencemicrobial communitieszooxanthellaeReview01 natural sciences03 medical and health sciencesCnidariaantibacterial activityPhylogeneticsImmunityAnthozoaDrug DiscoveryHomeostasiAnimalsHomeostasisSymbiosiscnidarianPharmacology Toxicology and Pharmaceutics (miscellaneous)lcsh:QH301-705.5Phylogenymedia_commonInnate immune systemMucous MembranebiologyMechanism (biology)Animal010604 marine biology & hydrobiologyDrug Discovery3003 Pharmaceutical ScienceMicrobiotaLongevitybleachingcnidarian holobiontbiology.organism_classificationImmunity InnateHolobiont030104 developmental biologylcsh:Biology (General)Evolutionary biologyanthozoaSymbiosiBiotechnologyMarine Drugs
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Marine Cryptophytes Are Great Sources of EPA and DHA

2017

Microalgae have the ability to synthetize many compounds, some of which have been recognized as a source of functional ingredients for nutraceuticals with positive health effects. One well-known example is the long-chain polyunsaturated fatty acids (PUFAs), which are essential for human nutrition. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are the two most important long-chain omega-3 (-3) PUFAs involved in human physiology, and both industries are almost exclusively based on microalgae. In addition, algae produce phytosterols that reduce serum cholesterol. Here we determined the growth rates, biomass yields, PUFA and sterol content, and daily gain of eight strains of marine…

0106 biological sciences0301 basic medicineTROPICAL AUSTRALIAN MICROALGAELINOLENIC ACIDrasvahapotPharmaceutical Sciencesterols01 natural scienceschemistry.chemical_compoundFunctional FoodDrug DiscoveryFood scienceBiomasslcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)functional foodsPOLYUNSATURATED FATTY-ACIDSchemistry.chemical_classificationnutraceuticalsFRESH-WATERPRODUCTIVITYbiologymicroalgae; polyunsaturated fatty acids; omega-3; omega-6; sterols; functional foods; nutraceuticalsCHOLESTEROLmicroalgaeNANNOCHLOROPSISPhytosterolsfood and beveragesEicosapentaenoic acidEicosapentaenoic AcidDocosahexaenoic acidFatty Acids Unsaturatedlipids (amino acids peptides and proteins)omega-3CryptophytaPolyunsaturated fatty acidpolyunsaturated fatty acidsDocosahexaenoic Acidsomega-6CHEMICAL-COMPOSITIONterveysvaikutteiset elintarvikkeetfatty acidsGas Chromatography-Mass SpectrometryArticleMARICULTURE03 medical and health sciencesNutraceuticalAlgaeFatty Acids Omega-6Fatty Acids Omega-31172 Environmental sciencessterolit010604 marine biology & hydrobiologyomega fatty acidsta1183ta1182GROWTH-RATEmikrolevätbiology.organism_classificationSterolomegarasvahapot030104 developmental biologyHuman nutrition416 Food Sciencelcsh:Biology (General)chemistry13. Climate actionDietary SupplementsStearidonic acidMarine Drugs; Volume 16; Issue 1; Pages: 3
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Anthocyanins of Coloured Wheat Genotypes in Specific Response to SalStress

2018

The present study investigated the effect of salt stress on the development of adaptive responses and growth parameters of different coloured wheat genotypes. The different coloured wheat genotypes have revealed variation in the anthocyanin content, which may affect the development of adaptive responses under increasing salinity stress. In the early stage of treatment with salt at a lower NaCl concentration (100 mM), anthocyanins and proline accumulate, which shows rapid development of the stress reaction. A dose-dependent increase in flavonol content was observed for wheat genotypes with more intense purple-blue pigmentation after treatment with 150 mM and 200 mM NaCl. The content of Na⁺ a…

0106 biological sciences0301 basic medicineflavonolMDAColorPharmaceutical ScienceSodium Chloride01 natural sciencesArticleSalinity stressAnalytical Chemistrysalinitylcsh:QD241-44103 medical and health scienceschemistry.chemical_compoundlcsh:Organic chemistryDry weightStress PhysiologicalwheatDrug DiscoveryGenotypeDry matterProlinePhysical and Theoretical ChemistryprolineTriticumPigmentationChemistryOrganic Chemistryfood and beveragesSalt ToleranceanthocyaninsSalinityHorticulture030104 developmental biologyChemistry (miscellaneous)AnthocyaninMolecular MedicineAfter treatment010606 plant biology & botanyMolecules
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Comparison of Diatoms and Dinoflagellates from Different Habitats as Sources of PUFAs

2019

Recent studies have clearly shown the importance of omega-3 (&omega

0106 biological sciencesALPHA-LINOLENIC ACIDrasvahapotPharmaceutical ScienceFresh Water01 natural sciencesFATTY-ACID-COMPOSITIONchemistry.chemical_compoundDrug DiscoveryFood sciencefreshwaterlcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)chemistry.chemical_classification0303 health sciencespanssarilevätFRESH-WATERalpha-Linolenic acidmicroalgaeFatty AcidsFish oilEicosapentaenoic acid6. Clean waterDHADocosahexaenoic acidEUTROPHICATIONDinoflagellidaGROWTHdinoflagellatesbrackishPolyunsaturated fatty acidpolyunsaturated fatty acidsTOXINBiologyPROFILEArticlediatoms03 medical and health sciencesFish OilsFISHFatty Acids Omega-3PhytoplanktonpiilevätQUALITYSaline WatersEcosystem030304 developmental biologyBrackish water010604 marine biology & hydrobiologyfungita1183ta1182Fatty acidmarineEPAmikrolevätluonnonaineetomegarasvahapotmerivesilcsh:Biology (General)chemistry416 Food Science13. Climate actionmakea vesiMarine Drugs
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Control of Erigeron bonariensis with Thymbra capitata, Mentha piperita, Eucalyptus camaldulensis, and Santolina chamaecyparissus Essential Oils

2020

In the search of sustainable and environmentally friendly methods for weed control, there is increasing interest in essential oils (EOs) as an approach to reduce synthetic herbicide use. The phytotoxicity of Thymbra capitata, Mentha piperita, Eucalyptus camaldulensis, and Santolina chamaecyparissus EOs against the noxious weed Erigeron bonariensis were evaluated in pre- and post-emergence assays in greenhouse conditions. The EOs were applied at 2, 4, and 8 &micro

0106 biological sciencesAgricultural IrrigationErigeronPharmaceutical SciencePlant WeedsAsteraceae01 natural sciencesEssential oilAnalytical ChemistrySantolina chamaecyparissusPlantletDrug DiscoveryErigeron bonariensisEucalyptusbiologyNoxious weedMentha piperita04 agricultural and veterinary sciences<i>erigeron bonariensis</i>Weed controlSettore AGR/02 - Agronomia E Coltivazioni ErbaceeHorticultureChemistry (miscellaneous)GerminationEssential oilsMolecular MedicinePhytotoxicityPre-emergenceBOTANICAGerminationArticlelcsh:QD241-441lcsh:Organic chemistryQUIMICA ANALITICAOils VolatilePlant OilsPost-emergencePhysical and Theoretical ChemistryErigeron bonariensiLamiaceaeDose-Response Relationship DrugOrganic Chemistrybiology.organism_classificationSeed germinationNatural herbicideErigeronEucalyptus camaldulensisEmulsifying AgentsCapitata040103 agronomy & agriculture0401 agriculture forestry and fisheriesNatural herbicides010606 plant biology & botany
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Herbicidal activity of Thymbra capitata (L.) Cav. essential oil

2020

The bioherbicidal potential of Thymbra capitata (l.) Cav. essential oil (EO) and its main compound carvacrol was investigated. In in vitro assays, the EO blocked the germination and seedling growth of Erigeron canadensis L., Sonchus oleraceus (l.) L., and Chenopodium album L. at 0.125 &micro

0106 biological sciencesAvenaPharmaceutical ScienceIntegrated weed managementSolanum nigrum3101.06 Herbicidas01 natural sciencesAnalytical Chemistrylaw.inventionchemistry.chemical_compoundbioherbicideslawDrug Discovery2302.10 Aceites Esencialesnatural herbicidesCarvacrol0303 health sciencesSetaria verticillatabiologyChenopodium3103.15 Control de MalezasWeed controlSettore AGR/02 - Agronomia E Coltivazioni Erbacee02.- Poner fin al hambre conseguir la seguridad alimentaria y una mejor nutrición y promover la agricultura sostenibleHorticultureChemistry (miscellaneous)Essential oilsintegrated weed managementMolecular Medicineweed controlSettore AGR/13 - Chimica AgrariaBOTANICAcarvacrolPortulacanatural herbicideThymbra capitataessential oilArticlelcsh:QD241-44103 medical and health sciencesBioherbicideslcsh:Organic chemistryCarvacrolOils VolatilePhysical and Theoretical ChemistryAvena fatuaessential oilsEssential oil030304 developmental biologyLamiaceaeHerbicidesOrganic Chemistrybiology.organism_classificationSonchus oleraceuschemistrySeedlingsEchinochloaCapitataNatural herbicides010606 plant biology & botany
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Improved Extraction Efficiency of Antioxidant Bioactive Compounds from Tetraselmis chuii and Phaedoactylum tricornutum Using Pulsed Electric Fields

2020

Pulsed electric fields (PEF) is a promising technology that allows the selective extraction of high-added value compounds by electroporation. Thus, PEF provides numerous opportunities for the energy efficient isolation of valuable microalgal bioactive substances (i.e., pigments and polyphenols). The efficiency of PEF-assisted extraction combined with aqueous or dimethyl sulfoxide (DMSO) solvents in recovering pigments and polyphenols from microalgae Tetraselmis chuii (T. chuii) and Phaeodactylum tricornutum (P. tricornutum) was evaluated. Two PEF treatments were applied: (1 kV/cm/400 pulses, 3 kV/cm/45 pulses), with a specific energy input of 100 kJ/kg. The total antioxidant capacity (TAC) …

0106 biological sciencesChlorophyll bAntioxidantmedicine.medical_treatmentPharmaceutical ScienceTetraselmis chuii01 natural sciencesPhaeodactylum tricornutumArticleAntioxidantsAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compound0404 agricultural biotechnologylcsh:Organic chemistryChlorophyta010608 biotechnologyDrug DiscoverymedicineMicroalgaePhaeodactylum tricornutum<i>Phaeodactylum tricornutum</i>Physical and Theoretical ChemistryTetraselmis<i>Tetraselmis chuii</i>Carotenoidchemistry.chemical_classificationDiatomsChromatographybiologyChemistryDimethyl sulfoxideOrganic ChemistryExtraction (chemistry)Polyphenols04 agricultural and veterinary sciencesbiology.organism_classification040401 food science6. Clean waterElectroporationpulsed electric fieldsChemistry (miscellaneous)PolyphenolextractionMolecular Medicineantioxidant bioactive compoundsMolecules
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Influence of the Storage of Cistus ladanifer L. Bales from Mechanised Harvesting on the Essential Oil Yield and Qualitative Composition

2021

Cistus ladanifer is a Mediterranean native plant from which valuable products, such as essential oil, are obtained. Manual harvesting of the plants in wild shrublands is usual during short periods of time. Their mechanised harvesting could increase the volume of harvested plants and prevent fires, further storage of the plants collected being necessary. The objective of this work is to study the influence of the storage period of mechanically harvested bales on the essential oil yield and qualitative composition. The harvesting trials were carried out with an adapted commercial harvester baler and the storage of the bales was performed indoors during 1–7 days, 15–30 days and 100–120 days. A…

0106 biological sciencesChromatography Gasdistillation020209 energyPharmaceutical ScienceBiomassOrganic chemistry02 engineering and technology01 natural sciencesCistus ladaniferGas Chromatography-Mass SpectrometryArticleessential oilAnalytical Chemistrylaw.inventionSteam distillationmechanised harvestingQD241-441<i>Cistus ladanifer</i> L.lawDrug Discovery0202 electrical engineering electronic engineering information engineeringOils VolatilePhysical and Theoretical ChemistryDistillationEssential oilbiologySuperheated steamCistusbiology.organism_classificationrockroseHorticulturePilot plantChemistry (miscellaneous)pilot plantMonoterpenesMolecular MedicineEnvironmental scienceComposition (visual arts)Cistus ladanifer L.010606 plant biology & botanyMolecules
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